Skip to content

Visiting 43North at Seneca One





43North is located on the 24th floor of Seneca One. Below is the building address and helpful tips for parking and finding your way inside.

1 Seneca Street, FL 24
Buffalo, NY 14203

Parking Directions

The Seneca One parking garage is located at 50 Exchange Street. On the third level, there is a bridge that will take you directly to Seneca One’s East entrance at the rear of the building. Once you’re over the bridge, enter the building on the right (if you’ve reached the Metro Rail, you’ve gone too far).

Once inside the building, you will see elevators on your left, or you can keep walking straight to the escalators. Take either up to the lobby level.

Street parking is also available around the perimeter of the building. Please note that you do have to pay during certain times of the day. Payments can be made through the Buffalo Roam app (check the sign near your parking spot for the zone #).

Other ways to get here

School bus or limo – Buses can park on Seneca Street. Visitors will enter at the West entrance.

Ride Share – Have your driver drop you off in front of the building on Seneca Street. Visitors will enter at the West entrance.

NFTA Rail – Please get off at the Seneca Street Station which is a 30 second walk to SO.

NFTA Bus – Please get off at the Washington Street Station which is a 30 second walk to SO.

Train – Buffalo’s AMTRAK station is directly behind Seneca One. Getting Inside the Building


Seneca One has four entrances on the Seneca St level. Two are in the “front” of the building on either side of Main Street and two are in the back. The “front” entrances at Main and Seneca St are always open during business hours. Entrances in the back of the building and connected through the parking garage are typically open and accessible from 9 am – 5 pm, and during major events.

Once you enter the building, take the elevators or escalators up to the lobby level.

Tags: Contact, Seneca One

More blog posts

Our Application is Now Open!

Apply to 43North’s Accelerator Program Today Hey, seed-stage founders! Our 2024 application is now open. Sharpen your edge with $1 million in funding, expert mentorship, invaluable connections, and an immersive accelerator program like no other.  Now in our 10th year, our track record speaks volumes: with 69 startups in our portfolio and an IPO under

Charging Ahead: Jane Chen’s Electrical Revolution with StepWise

In this episode of the Latitude podcast by 43North, Justine Palkowski, Senior Marketing Manager, hosts the co-founders of Stepwise, a Y9 cohort company that recently relocated to Buffalo. Stepwise aims to revolutionize electrification, making it affordable and accessible for homeowners. Meet the Team: Jane Chen, Co-founder and CEO, brings a business background and a passion

Phenomenal Ventures Managing Partner, Helen Min on the 43North Latitude Podcast Graphic
Leaning into Your Strengths for Entrepreneurial Success

Discover the keys to entrepreneurial success as Helen Min, Managing Partner at Phenomenal Ventures, shares insights on playing to your strengths in the startup world. Helen, a Buffalo native with a background in major tech companies and advertising, discusses the evolving role of AI, the power of complementary strengths in founding teams, and the crucial